c 4 -hsl Search Results


n -butanoyl- l -homoserine lactone (c4-ahl)  (Cayman Chemical)
90
Cayman Chemical n -butanoyl- l -homoserine lactone (c4-ahl)
N Butanoyl L Homoserine Lactone (C4 Ahl), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pmc07343617-265-1-19?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
n -butanoyl- l -homoserine lactone (c4-ahl) - by Bioz Stars, 2026-08
90/100 stars
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c 4 -hsl  (Cayman Chemical)
90
Cayman Chemical c 4 -hsl
C 4 Hsl, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pmc11112094-118-0-16?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
c 4 -hsl - by Bioz Stars, 2026-08
90/100 stars
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n-(octanoyl)-l-homoserine lactone (c8-hsl)  (Quorum Sciences Inc)
90
Quorum Sciences Inc n-(octanoyl)-l-homoserine lactone (c8-hsl)
N (Octanoyl) L Homoserine Lactone (C8 Hsl), supplied by Quorum Sciences Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/10__1128_slash_aem__71__5__2632___2641__2005-101-3-23?v=Quorum+Sciences+Inc
Average 90 stars, based on 1 article reviews
n-(octanoyl)-l-homoserine lactone (c8-hsl) - by Bioz Stars, 2026-08
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n-butanoyl homoserine lactone (c4-hsl)  (NCIMB Ltd)
90
NCIMB Ltd n-butanoyl homoserine lactone (c4-hsl)
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
N Butanoyl Homoserine Lactone (C4 Hsl), supplied by NCIMB Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pmc05247445-203-26-11?v=NCIMB+Ltd
Average 90 stars, based on 1 article reviews
n-butanoyl homoserine lactone (c4-hsl) - by Bioz Stars, 2026-08
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c4-hsl stock solution  (NARD Institute Ltd)
90
NARD Institute Ltd c4-hsl stock solution
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
C4 Hsl Stock Solution, supplied by NARD Institute Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pm28120378-171-14-9?v=NARD+Institute+Ltd
Average 90 stars, based on 1 article reviews
c4-hsl stock solution - by Bioz Stars, 2026-08
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n-butyryl-l-homoserine lactone (c4-hsl)  (ApexBio)
90
ApexBio n-butyryl-l-homoserine lactone (c4-hsl)
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
N Butyryl L Homoserine Lactone (C4 Hsl), supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pmc10879701-14-0-4?v=ApexBio
Average 90 stars, based on 1 article reviews
n-butyryl-l-homoserine lactone (c4-hsl) - by Bioz Stars, 2026-08
90/100 stars
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c4-hsl (10 m  (Cayman Chemical)
90
Cayman Chemical c4-hsl (10 m
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
C4 Hsl (10 M, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/10__1128_slash_jb__01528___09-62-4-7?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
c4-hsl (10 m - by Bioz Stars, 2026-08
90/100 stars
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n-(butanoyl)-l-homoserine lactone (c4-hsl)  (Quorum Sciences Inc)
90
Quorum Sciences Inc n-(butanoyl)-l-homoserine lactone (c4-hsl)
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
N (Butanoyl) L Homoserine Lactone (C4 Hsl), supplied by Quorum Sciences Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/10__1128_slash_aem__71__5__2632___2641__2005-101-1-23?v=Quorum+Sciences+Inc
Average 90 stars, based on 1 article reviews
n-(butanoyl)-l-homoserine lactone (c4-hsl) - by Bioz Stars, 2026-08
90/100 stars
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n-acyl-homoserine lactones c4-hsl  (Quorum Sciences Inc)
90
Quorum Sciences Inc n-acyl-homoserine lactones c4-hsl
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
N Acyl Homoserine Lactones C4 Hsl, supplied by Quorum Sciences Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/10__1128_slash_jb__185__20__5976___5983__2003-63-0-8?v=Quorum+Sciences+Inc
Average 90 stars, based on 1 article reviews
n-acyl-homoserine lactones c4-hsl - by Bioz Stars, 2026-08
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c 4 -hsl #10007898  (Cayman Chemical)
90
Cayman Chemical c 4 -hsl #10007898
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
C 4 Hsl #10007898, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pmc06202348-190-2-14?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
c 4 -hsl #10007898 - by Bioz Stars, 2026-08
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n -butyryl- l -homoserine lactone (c4-hsl)  (NCIMB Ltd)
90
NCIMB Ltd n -butyryl- l -homoserine lactone (c4-hsl)
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
N Butyryl L Homoserine Lactone (C4 Hsl), supplied by NCIMB Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pmc07763822-495-20-16?v=NCIMB+Ltd
Average 90 stars, based on 1 article reviews
n -butyryl- l -homoserine lactone (c4-hsl) - by Bioz Stars, 2026-08
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ahl activity assay c4-hsl  (Cayman Chemical)
90
Cayman Chemical ahl activity assay c4-hsl
Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of <t>acyl-homoserine</t> lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).
Ahl Activity Assay C4 Hsl, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c+4+-hsl/pm25044227-209-3-12?v=Cayman+Chemical
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ahl activity assay c4-hsl - by Bioz Stars, 2026-08
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Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of acyl-homoserine lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).

Journal: Frontiers in Microbiology

Article Title: The Social Life of Aeromonas through Biofilm and Quorum Sensing Systems

doi: 10.3389/fmicb.2017.00037

Figure Lengend Snippet: Schematic representation of AI-1 quorum sensing system in Aeromonas . From an in vitro model of autoinducer 1 (AI-1) quorum sensing system of A. hydrophila , Garde et al. have distinguished two phases since the complex AI-1/receptor (AhyR) activates the quorum sensing loop of the initial AI-1 producer bacterial cell during exponential growth (A) or of other bacterial cells during the stationary phase (B) due to slow decay of the complex AI-1/receptor (AhyR). (A) Autoinduction occurs during exponential growth phase (Garde et al., ). In this phase, the enzyme (E) AhyI synthetizes AI-1 signal molecules of acyl-homoserine lactones (AHL) from S-adenosyl-methionine (SAM) and acyl–acyl carrier proteins (acyl) (Swift et al., ; Parsek et al., ). The protein AhyR is the sensor (S) of the AI-1 system and is activated by AHL molecules (Swift et al., ). Once activated, AhyR is a transcriptional regulator for the ahyRI locus encompassing AhyI and AhyR encoding genes, and participates in the auto-amplification loop (Kirke et al., ; Garde et al., ). The transcription of ahyRI locus is also likely enhanced (discontinuous traits) by the second messenger c-di-GMP and by AI-2 synthase LuxS or by AI-3 transcriptional regulatory protein QseB (Kozlova et al., ). The AHL molecules are freely diffusible across bacterial membranes and accumulate in the extracellular environment (Garde et al., ). (B) Intercellular activation occurs over an AHL concentration threshold corresponding to high cell density occurring at the stationary phase (Garde et al., ). Once activated by AHL molecules, AhyR is a transcriptional regulator for several genes associated to virulence and biofilm formation. In contrast to its action during the autoinduction phase, activated-AhyR negatively regulates the transcription of the ahyRI locus (Kirke et al., ). This AI-1 system is inhibited by exogenous long chain AHL or furanones (Swift et al., ; Ponnusamy et al., ) that may act as competitive inhibitors of AHL for AhyR binding. The AI-1 quorum sensing system negatively regulates the transcription of luxS and qseBC loci, encoding AI-2 synthase and AI-3 two components system, respectively (Kozlova et al., , ).

Article Snippet: Culture supernatants of A. hydrophila AH-1 and A. salmonicida type strain NCIMB 1102 T , as studied by bioassays and high-performance liquid chromatography (HPLC), showed that N-butanoyl homoserine lactone (C4-HSL), and N-hexanoyl homoserine lactone (C6-HSL) are the major autoinducers produced by aeromonads, and the ratio C4:C6 is 70:1 (Swift et al., ).

Techniques: In Vitro, Amplification, Activation Assay, Concentration Assay, Binding Assay

Types of N-acyl homoserine lactone (AHL) produced by Aeromonas species from different isolation origins regarding the methods used for AHL analysis .

Journal: Frontiers in Microbiology

Article Title: The Social Life of Aeromonas through Biofilm and Quorum Sensing Systems

doi: 10.3389/fmicb.2017.00037

Figure Lengend Snippet: Types of N-acyl homoserine lactone (AHL) produced by Aeromonas species from different isolation origins regarding the methods used for AHL analysis .

Article Snippet: Culture supernatants of A. hydrophila AH-1 and A. salmonicida type strain NCIMB 1102 T , as studied by bioassays and high-performance liquid chromatography (HPLC), showed that N-butanoyl homoserine lactone (C4-HSL), and N-hexanoyl homoserine lactone (C6-HSL) are the major autoinducers produced by aeromonads, and the ratio C4:C6 is 70:1 (Swift et al., ).

Techniques: Produced, Isolation